Spider-Man is swinging across the city to make it to the New York Hospital, there he changes back to Peter Parker to visit his Aunt May before she is taken off to an old folks home. After May is taken away, her doctor makes a rude comment about how Peter won't have to worry about her and Peter loses his temper and almost punches him with his spider-strength before checking himself and leaving the scene.
While at the Daily Bugle, J. Jonah Jameson becomes furious that none of his reporters or the authorities can find out what happened to his son and storms out of the Bugle office. Unknown to either him or Spider-Man, a shadowed figure and a mummified man are plotting to get revenge against both of them. Jameson goes to visit Marla Madison and tells her of his recent troubles and she comforts him.

As Spider-Man breaks up an attempted robbery that is surrounded by the police. The police are less than happy about Spider-Man's involvement because they has the situation under control. Meanwhile, Jameson goes to visit District Attorney Blake Tower to demand he do more, when Blake cannot do so, Jameson decides to put out ads offering a reward for John's safe return. Jameson is too busy with this campaign to overly care about Robbie's lead on a shipment of stolen plutonium.

This plutonium has been stolen by the mystery man gunning for both the wall-crawler and crotchety publisher and is using it to power his equipment in his secret Westchester headquarters to irradiate his mummified soldier. While back at Peter Parker's apartment, Betty drops in on Peter and the two talk about their relationship in light of her separation from Ned Leeds. This leads to Betty kissing Peter, telling him that she wants to leave Ned for good because she is still in love with Parker.

Later, changing into Spider-Man, Peter web-slings across the city and happens upon the mummy attacking the Daily Bugle building and going after J. Jonah Jameson. Spidey tries to stop the foe and finds him super strong. In the scuffle over Jameson, the bandages on the attackers body unravel revealing it's true identity: The Man-Wolf. Shocked by this revelation, Spider-Man is distracted enough to be knocked out by one of the Man-Wolf's blows, the creature then grabs Jameson and flees the scene with his own father as captor.

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