1) Crisis! 2) The End of The ANCIENT ONE!
1) Strucker announces that the impregnable dome over Hydra Island will keep them safe from the "Death Spore" plague, and plans to use Fury's body as the basis for an army of HYDRA androids to "police" the world, once he's dead from the Alpha Ray beam. But Fury escapes! As SHIELD searches the Heli-Carrier for the bomb with no result, Fury, "playing it by ear", takes on one group of HYDRA thugs after another, until Strucker faces him one-on-one. Thanks to his deadly "Satan Claw", Strucker gains the upper hand, and it looks like it might be the end.
1st Appearance "Living Tribunal" (The Caretaker of The Multiverse)
2) To defeat Umar, Doctor Strange freed Zom, who has trapped him and the Ancient One in the Seven Bands of Cyttorak. The Ancient One sacrifices himself to pass his powers on to Strange; while merging with a stone pillar, he warns of "the coming of" something and says, "the forelock." Zom casts a spatial distortion spell, which Strange escapes with his new strength. Strange grasps Zom's topknot and pulls it loose, at the cost of part of his cloak. Zom seems afraid, as do the mystically attuned of Earth (shown by the All-Seeing Eye of Agamotto). Zom traps Strange in another spell but is dissolved by the coming of ... the Living Tribunal. Because of Strange, Earth's mystics now have a "sense of evil," so their world must be destroyed.