Weapons of Mutant Destruction tells about the renewed Weapon X program led by Reverend Stryker. They track down mutants with cyborgs encased in human skin and obtain DNA samples. They use those samples to blend together various mutant's abilities. When Logan was attacked he set out forming a team to fight the cyborgs. The Weapon X team was Logan, Sabretooth, Lady Deathstrike, Domino, Warpath, the Totally Awesome Hulk and near the end the all-new Wolverine. The end result was a potential world breaker, a Hulkverine, code name Weapon H.