Yandroth, an alien scientist, clashed with Doctor Strange multiple times. After being defeated by Strange, Yandroth fell into an alternate dimension. There, he discovered that destroying a world could grant him immense power. He created the ‘Omegatron,’ later defeated by the Defenders. Yandroth’s spirit persisted, possessing a young girl and plotting to end the world. He used Gaea’s form to summon monsters, leading to a battle with the Defenders. Ultimately, Yandroth’s curse forced them to work together during crises. Later, he was revived and continued his vendetta against various superhero teams.